MedPage Today - Men with high-risk localized prostate cancer had similar survival with surgery or with the combination of external beam radiotherapy (EBRT) plus brachytherapy, according to a retrospective review of more than 40,000 cases.
After adjustment for lymph node status, Gleason score, clinical T stage, and other factors, the resulting survival hazard for radical prostatectomy versus combined radiation therapy did not achieve statistical significance and numerically favored the nonsurgical approach (HR 1.17, 95% CI 0.88-1.55). The addition of androgen deprivation therapy (ADT) to radiotherapy did not improve survival as compared with EBRT plus brachytherapy without ADT...>>>
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